News Curated �鶹��ý Channel: Grant Funded News

New Study Sheds Light on How Bacteria 'Vaccinate' Themselves with Genetic Material from Dormant Viruses

Johns Hopkins Medicine — Fri, 21 Mar 2025 17:45:44 EST

Johns Hopkins Medicine scientists say they have shed new light on how bacteria protect themselves from certain phage invaders -- by seizing genetic material from weakened, dormant phages and using it to "vaccinate" themselves to elicit an immune response.

Scientists Witness Living Plant Cells Generate Cellulose and Form Cell Walls For the First Time

Rutgers University-New Brunswick — Fri, 21 Mar 2025 14:00:00 EST

In a groundbreaking study on the synthesis of cellulose - a major constituent of all plant cell walls - a team of Rutgers University-New Brunswick researchers has captured images of the microscopic process of cell-wall building continuously over 24 hours with living plant cells, providing critical insights that may lead to the development of more robust plants for increased food and lower-cost biofuels production.

Scientists Demonstrate Pre-clinical Proof of Concept for Next-Gen DNA Delivery Technology

Wistar Institute — Fri, 21 Mar 2025 11:05:00 EST

Wistar Institute scientists and collaborators describe a next-generation vaccination technology that combines plasmid DNA with a lipid nanoparticle delivery system.

Boosting Brain's Waste Removal System Improves Memory in Old Mice

Washington University in St. Louis — Fri, 21 Mar 2025 11:00:00 EST

Aging compromises the lymphatic vessels surrounding the brain, disabling waste drainage from the brain and impacting cognitive function. Researchers at WashU Medicine boosted lymphatic vessel integrity in old mice and found improvements in their memory compared with old mice without rejuvenated lymphatic vessels.

A CSUF Study on Tiny Vinegar Eelworms Could Help Researchers Aid Advancements in the Biomedical and Biophysics Fields

California State University, Fullerton — Thu, 20 Mar 2025 18:35:41 EST

Tiny nematodes, commonly known as vinegar eelworms, can move objects with a force hundreds of times their own weight.

New Rules for the Game of Memory

University of Chicago Medical Center — Thu, 20 Mar 2025 18:00:27 EST

New research from UChicago upends traditional views on how synaptic plasticity supports memory and learning.

Xylazine Detected in U.S.-Mexico Border Drug Supply, Study Finds

University of California San Diego — Thu, 20 Mar 2025 11:00:00 EST

Researchers at UC San Diego have confirmed the presence of xylazine in the illicit drug supply at the U.S.-Mexico border. While xylazine remains less common in the Western U.S., border cities serve as key trafficking hubs and may have higher rates of emerging substances.

Removing a Protein 'Signal Jammer' Improves Immunotherapy

St. Jude Children's Research Hospital — Wed, 19 Mar 2025 19:55:58 EST

Find how a mitochondrial protein protects cancer cells from immunotherapy, giving scientists a new target type to improve solid tumor treatment & save lives.

Anti-Amyloid Drug Shows Signs of Preventing Alzheimer's Dementia

Washington University in St. Louis — Wed, 19 Mar 2025 19:30:00 EST

An experimental drug appears to reduce the risk of Alzheimer's-related dementia in people destined to develop the disease in their 30s, 40s or 50s, according to the results of a study led by the Knight Family Dominantly Inherited Alzheimer Network-Trials Unit (DIAN-TU), which is based at WashU Medicine.

Researchers Find Missing Link in Autoimmune Disorder

Washington University in St. Louis — Tue, 18 Mar 2025 20:55:25 EST

Scientists at Washington University School of Medicine in St. Louis and the Perelman School of Medicine at the University of Pennsylvania have identified a key component to launching immune activity - and overactivity. The researchers identified a protein in cells that spurs the release of infection-fighting molecules. The protein, whose role in the immune system had not previously been suspected, provides a potential target for therapies that could prevent overreactive immune responses that are at the root of several debilitating illnesses.

Charging Toward Greener Chemicals

Iowa State University — Tue, 18 Mar 2025 20:35:14 EST

Iowa State researchers are combining bio-based reactions with electricity-driven reactions as a potential step toward transforming chemical manufacturing to a greener industry that's less dependent on petroleum-based materials and the need to process them with high energies, temperatures and emissions.

Moffitt Study Finds Vaccine May Improve Breast Cancer Treatment Outcomes

Moffitt Cancer Center — Tue, 18 Mar 2025 20:25:56 EST

Moffitt Cancer Center researchers have discovered a promising new vaccine strategy for treating a specific type of breast cancer. The innovative approach targets human epidermal growth factor receptor 2-positive, estrogen receptor-negative (HER2-positive, ER-negative) breast cancer and has shown encouraging results in a recent pilot study. Published in npj Breast Cancer, the study combined the HER2-targeting dendritic cell vaccines with standard chemotherapy, demonstrating both safety and positive response rates.

Study Confirms Safety and Efficacy of Higher-Dose-Per-Day Radiation for Early-Stage Prostate Cancer

University of California, Los Angeles (UCLA), Health Sciences — Tue, 18 Mar 2025 18:40:09 EST

A new large-scale study provides the strongest evidence yet that a shorter, standard-dose course radiation treatment is just as effective as conventional radiotherapy for prostate cancer, without compromising the safety of patients.

Wayne State University Research Making Strides in Autonomous Vehicle and Machine Systems to Make Them Safer, More Effective

Wayne State University Division of Research — Tue, 18 Mar 2025 18:20:30 EST

A grant to Wayne State University from the National Science Foundation (NSF) is opening new doors for researchers and students to explore the future of autonomous vehicles, machines and drones. Zheng Dong, Ph.D., assistant professor of computer science in Wayne State's School of Engineering, was awarded a five-year, $595,611 NSF grant for the project, "CAREER: ChronosDrive: Ensuring Timing Correctness in DNN-Driven Autonomous Vehicles with Accelerator-Enhanced Real-Time SoC Integration."

Anti-obesity medication boosts weight loss when behavioral therapy falls short

Perelman School of Medicine at the University of Pennsylvania — Tue, 18 Mar 2025 17:40:49 EST

Adding an anti-obesity medication just one month after behavioral therapy begins--rather than waiting the currently recommended six months--can more than double weight loss for patients who struggle initially with lifestyle changes alone, according to new research published in Nature Medicine from a team at the Perelman School of Medicine at the University of Pennsylvania.

Rising Stars: PPPL Researchers Honored in 2024 Physics of Plasmas Early Career Collection

Princeton Plasma Physics Laboratory — Tue, 18 Mar 2025 08:30:23 EST

Research by Frances Kraus, Jason Parisi and Willca Villafana will be featured in the Physics of Plasmas Early Career Collection.

Current Antivirals Likely Less Effective Against Severe Infection Caused by Bird Flu Virus in Cows' Milk

St. Jude Children's Research Hospital — Mon, 17 Mar 2025 19:45:43 EST

Existing antivirals may be less effective against this H5N1 bird flu strain, and prevention measures, such as avoiding raw milk consumption and reducing exposure in dairy workers, may be the most effective way to protect against the virus.

Dr. Theodore Scott Nowicki Awarded $4.5M NCI Grant to Advance Next Generation of Cellular Immunotherapies for Solid Tumors

University of California, Los Angeles (UCLA), Health Sciences — Mon, 17 Mar 2025 18:05:17 EST

Physician-scientist Theodore Scott Nowicki, MD, PhD, an assistant professor-in-residence of pediatric hematology/oncology and microbiology, immunology, & molecular genetics at the David Geffen School of Medicine at UCLA, has been awarded a $4.5 million R37 MERIT Award to help improve the effectiveness of cellular therapies for solid tumors.

Protein Plays Dual Role in Causing, Preventing Sepsis

UT Southwestern Medical Center — Mon, 17 Mar 2025 11:15:52 EST

A protein called angiopoietin-2 (ANGPT2) can both inhibit and encourage blood vessel changes critical for sepsis, a leading cause of hospital deaths worldwide, a new study led by UT Southwestern Medical Center researchers shows.

A Post-Treatment Blood Test Could Inform Future Cancer Therapy Decisions

Yale Cancer Center/Smilow Cancer Hospital — Mon, 17 Mar 2025 08:25:22 EST

A new study led by Dr. Roy Herbst, deputy director of Yale Cancer Center, found evidence to support the value of a tool that measures the presence of cancer-derived molecules in the blood of patients with lung cancer, years after their treatment.