News Curated �鶹��ý Channel: NEJM

AI Algorithm Can Help Identify High-Risk Heart Patients to Quickly Diagnose, Expedite, and Improve Care

Mount Sinai Health System — Tue, 22 Apr 2025 09:00:00 EST

Mount Sinai-led research can transform how hospitals triage, risk-stratify, and counsel patients to save lives

Multi-Center Study Uncovers Genetic Underpinnings of Congenital Diarrhea and Enteropathies

University of California, Los Angeles (UCLA), Health Sciences — Thu, 03 Apr 2025 09:10:53 EST

A new multi-center study co-led by scientists from UCLA Health has uncovered critical genetic insights into a group of rare disorders affecting intestinal epithelial cell function, paving the way for targeted therapies that could significantly improve patient outcomes.

Rethinking Shadowing for Aspiring Physicians: New Study Calls for More Inclusive and Structured Clinical Experiences

Uniformed Services University of the Health Sciences (USU) — Sat, 29 Mar 2025 07:30:00 EST

A new study from the Uniformed Services University (USU), "Rethinking Shadowing for Aspiring Physicians", published in the New England Journal of Medicine, challenges the traditional emphasis on physician shadowing as a key criterion for medical school admission, highlighting its financial and accessibility barriers for many aspiring doctors.

An Effective Antibiotic for Maternal Sepsis Saves Healthcare Costs

University of North Carolina School of Medicine — Wed, 26 Mar 2025 19:45:00 EST

An international cost-effectiveness study, led by researchers at the UNC School of Medicine and the Kinshasa School of Public Health, has found that an effective antibiotic used to combat maternal sepsis vastly reduces health-care costs for pregnant patients.

FDA Approves Dual-Action Drug for Patients with Previously Treated Advanced Neuroendocrine Tumors, Backed by Dana-Farber Research

Dana-Farber Cancer Institute — Wed, 26 Mar 2025 10:15:08 EST

The FDA approval was based on results from the CABINET study, a phase 3 pivotal trial evaluating cabozantinib compared with placebo in two groups of patients with previously treated NETs: advanced pancreatic NETs and advanced extra-pancreatic NETs. The study was led by Jennifer Chan, MD, MPH, clinical director of the gastrointestinal cancer center and director of the program in carcinoid and neuroendocrine tumors at Dana-Farber Cancer Institute.

Pair of Studies Identify Promising New Treatments for Ulcerative Colitis

University of Chicago Medical Center — Tue, 04 Mar 2025 19:05:44 EST

Two new drugs offer chance for patients who don't respond to existing treatments to break through the "therapeutic ceiling" for ulcerative colitis.

VUMC Part of New Study Validating Curative Therapy for Sickle Cell Disease

Vanderbilt University Medical Center — Tue, 04 Mar 2025 10:50:20 EST

A modified bone marrow transplant procedure for sickle cell disease (SCD) co-developed at Vanderbilt University Medical Center, Johns Hopkins University School of Medicine, and the University of California, San Francisco, can cure the disease, a new study has found.

Artificial Intelligence Helps Find Undiagnosed Liver Disease

Cedars-Sinai — Thu, 27 Feb 2025 19:10:40 EST

An artificial intelligence (AI) program can identify chronic liver disease from videos taken during a common heart test known as an echocardiogram, Cedars-Sinai investigators report.

Text Message Tool Addresses "Time Toxicity" for Cancer Patients

Perelman School of Medicine at the University of Pennsylvania — Wed, 19 Feb 2025 20:20:29 EST

A Penn Medicine pilot study shows it's possible to use digital technology to safely reduce the amount of time some patients with cancer spend receiving care.

Researchers Look for the Best Ways to Help People with HIV Quit Smoking

University of Chicago Medical Center — Mon, 17 Feb 2025 20:25:53 EST

Combining bupropion medication and a behavioral counseling program dramatically increased quit rates among people living with HIV who smoked.

New Options for People With Tricuspid Valve Disease

Cedars-Sinai — Thu, 13 Feb 2025 20:20:07 EST

People living with tricuspid valve disease are gaining more treatment options, driven by research from Cedars-Sinai investigators and collaborators at other leading medical institutions.

AI Tool Helps Find Life-Saving Medicine for Rare Disease

Perelman School of Medicine at the University of Pennsylvania — Wed, 05 Feb 2025 17:00:00 EST

Set to enter hospice care, a patient with idiopathic multicentric Castleman's disease is now in remission after treatment with a medication identified by an AI-guided analysis

How Do You Treat Rotator-Cuff Tears?

Michigan Medicine - University of Michigan — Mon, 03 Feb 2025 20:55:52 EST

Shoulder symptoms led to an average of 9.6 million physician visits in 2015 and 2016 in the United States.The most common cause of those shoulder symptoms?Rotator-cuff disorders.Tears of the rotator cuff can result from a substantial traumatic injury or can occur slowly over time.

Study Finds Three New Safe, Effective Ways To Treat Drug-Resistant Tuberculosis

Harvard Medical School — Wed, 29 Jan 2025 17:00:00 EST

* Study finds three new safe and effective drug regimens to fight multidrug-resistant TB * The treatments, which include recently discovered TB drugs, give new options for shorter, personalized treatment and are cleared for use for more people than ever

A Weekly Injection Could Replace Painful Daily Treatment for Rare Fat Disorder

Rutgers University-New Brunswick — Wed, 29 Jan 2025 17:00:00 EST

A diabetes drug may beat costly shots for patients with a rare genetic condition, according to a Rutgers Health study.

Clinical Trial to Study New Use for CAR T-cell Therapy: Treating Autoimmune Diseases

University of Chicago Medical Center — Tue, 21 Jan 2025 19:45:52 EST

The University of Chicago Medicine has launched a Phase 2 clinical trial to study how CAR T-cell therapy could be used to treat three autoimmune diseases.

Study Published in NEJM Catalyst Finds Patients Cared for by MedStar Health's Safe Babies Safe Moms Program Have Better Outcomes in Pregnancy, Delivery, and Postpartum

MedStar Health — Wed, 15 Jan 2025 09:55:20 EST

Women who were cared for by the MedStar Health D.C. Safe Babies Safe Moms program (SBSM) have better outcomes in pregnancy, delivery, and postpartum, according to a study published today in NEJM Catalyst Innovations in Care Delivery.

Study Finds Transfusing More Blood Reduces Risk of Death at Six Months in Heart-Attack Patients With Anemia

Rutgers University-New Brunswick — Mon, 23 Dec 2024 18:05:24 EST

A study led by Rutgers professor finds more liberal blood transfusions have more favorable results

Research Shows New Treatment Could Delay Cancer Progression in Patients with High-Risk Smoldering Multiple Myeloma

Mayo Clinic — Tue, 10 Dec 2024 14:05:51 EST

A new treatment is showing promise for people with high-risk smoldering multiple myeloma (SMM). This precancerous condition can progress to active multiple myeloma, a type of blood cancer. High-risk SMM carries a higher likelihood of progression.

New Research from Children's Hospital of Philadelphia to Transform Standard of Care Across the Globe for Newly Diagnosed Children with B-cell Acute Lymphoblastic Leukemia

Children's Hospital of Philadelphia — Sat, 07 Dec 2024 10:00:32 EST

Researchers at Children's Hospital of Philadelphia (CHOP) and the Children's Oncology Group (COG) announced the results of a Phase 3 study that demonstrated adding the bi-specific T-cell engager, blinatumomab, to chemotherapy for newly diagnosed National Cancer Institute (NCI) standard risk (SR) B-cell acute lymphoblastic leukemia (B-ALL) pediatric patients significantly improves survival outcomes. The results were published today in the New England Journal of Medicine and will be presented during the plenary session at the 66th American Society of Hematology (ASH) Annual Meeting & Exposition in San Diego on December 8.