Today, Penn Medicine celebrated the groundbreaking of the Roberts Proton Therapy Center at Penn Presbyterian Medical Center in University City, which is expected to open for patient care in late 2027.
Clear aligners have emerged as a popular alternative to traditional braces, offering aesthetic and comfort advantages. However, their unique biomechanical properties and material characteristics present distinct clinical challenges. A recent expert consensus provides comprehensive guidelines for optimizing clear aligner therapy (CAT), covering case selection, treatment principles, and clinical procedures. The study highlights the importance of tailored strategies for different tooth movements, such as molar distalization and arch expansion, and introduces a novel assessment tool to grade treatment difficulty. By addressing potential complications and emphasizing patient-specific approaches, this consensus aims to enhance treatment efficacy and broaden the adoption of clear aligners in orthodontic practice.
Researchers from The University of Texas MD Anderson Cancer Center will present promising results from clinical trials in three minisymposia abstracts at the American Association for Cancer Research (AACR) Annual Meeting 2025. Findings include a personalized vaccine combination therapy for colorectal cancer, the use of radiotherapy to avoid the toxicities of systemic treatments for kidney cancer, and engineered exosomes to silence mutant KRAS in pancreatic cancer.
Wren Laboratories, a leader in molecular diagnostics, is proud to announce that its breakthrough liquid biopsy test, PROSTest鈩�, has been approved by the New York State Department of Health Clinical Laboratory Evaluation Program (NYSDOH-CLEP).
In his fourth year of study in the University of Northern Colorado鈥檚 (UNC) Sport and Exercise Science Ph.D. 鈥� Exercise Physiology Concentration program, Edwin Rodriguez is embarking on research for cancer patients.
A newly identified subtype of Castleman disease will help diagnose and properly treat thousands of patients who have been caught between existing classification systems, marking the first major discovery of its kind in 45 years. "Oligocentric Castleman Disease" (OligoCD) has been found to be a distinct clinical entity, different from the two previously identified classifications of Castleman Disease. The findings, which redefine the understanding of this rare immune disorder that affects an estimated 4,300 to 5,200 Americans, are published this week in Blood Advances by researchers from the Perelman School of Medicine at the University of Pennsylvania.
Older adults with cancer respond just as well as younger patients to immune checkpoint inhibitors despite age-related immune system differences, according to a study by researchers from the聽Johns Hopkins Kimmel Cancer Center聽and its聽Bloomberg~Kimmel Institute for Cancer Immunotherapy,聽and the聽Johns Hopkins Convergence Institute. The study was supported in part by the National Institutes of Health, including the National Cancer Institute鈥檚 Specialized Programs of Research Excellence.
Research supports the effectiveness of a kinesiology-based method to treat lower back pain, say study authors working in collaboration with the National Research Council of Italy, and scientists at the Sbarro Health Research Organization under the leadership of its Founder and President, Antonio Giordano, M.D., Ph.D., Professor at Temple University.
Wound healing has been termed 鈥渁n overlooked burden and a silent epidemic鈥� due to the significant financial strain that it places on healthcare systems, let alone the unquantifiable human cost.
The annual meeting, which showcases cutting-edge cancer science and medicine, will feature UCLA-led research in key areas of both translational and basic scientific research. These include new combination immunotherapy approaches, updated organoid models, epigenetic markers for breast cancer risk and efforts to overcome drug resistance in liver cancer.
Research from the University of Portsmouth suggests that bras offering excessive bounce reduction may come with hidden consequences for spinal health.
Recent findings in bone regeneration research, highlights the significant impact of biological sex and donor variability on healing processes, offering promising new approaches to personalized medicine. By modeling cartilage-to-bone transition with innovative callus organoids, scientists discovered two distinct pathways鈥攈ypertrophic cartilage and fibrocartilage鈥攄riven by early progenitor cell activation.
When a critically ill infant is admitted to the Steven & Alexandra Cohen Foundation Newborn and Infant Critical Care Unit (NICCU) at Children鈥檚 Hospital Los Angeles, it can be for an underlying genetic cause for the baby鈥檚 symptoms. The hard part is locating the malfunction in the genes involved. To help with this process鈥攁nd better tailor a baby's treatment鈥擟HLA is now providing genome sequencing for infants who present with complex and rare conditions.
A new paper, published in Gene Therapy, raises serious concerns about the effectiveness of gene therapy for Duchenne muscular dystrophy (DMD), after the treatment failed to show significant benefit in a large-scale clinical trial.
A multicenter study led by Cedars-Sinai created a database of adverse medication events鈥攖he fourth leading cause of death in the United States and a medical issue costing more than $500 billion annually.
We鈥檙e pleased to announce Carolyn Mudry, D.O, has joined the Pascack Valley Medical Group family. With over 25 years of experience, Dr. Mudry brings a wealth of expertise in providing comprehensive, patient-centered care to the patients of Pascack Valley.
Atrial fibrillation (AFib) is the most common type of heart arrhythmia impacting more than 5 million people in the United States, a number that is anticipated to reach 12.1 million by 2030. The heart rhythm condition is characterized by fast and irregular heartbeats from the upper chambers of the heart. People with AFib are at increased risk of stroke, heart failure, dementia, and premature death.
Cedars-Sinai investigators have developed a novel artificial intelligence (AI) model, named DYNA, that accurately distinguishes harmful gene variations from harmless ones, potentially enhancing physicians鈥� ability to diagnose diseases. The new tool could pave the way for more precise personalized medicine and targeted therapies.
Biomedical researchers at Washington University in St. Louis have decoded how mechanical forces drive cell behavior in fibrosis.
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