Oral submucous fibrosis (OSF) is a serious disease that impairs mouth functionality, often leading to restricted opening and a high risk of malignant transformation. New research has uncovered a crucial player in this disease: cartilage oligomeric matrix protein (COMP).
Endometrial thickness plays an important role in successful embryo implantation and normal pregnancy achievement. However, a thin endometrial layer (鈮� 7 mm) may have a significant effect on microenvironment tolerance, which is further rel
Intervertebral disc degeneration is a leading cause of lower back pain and is characterized by pathological processes such as nucleus pulposus cell apoptosis, extracellular matrix imbalance, and annulus fibrosus rupture. These pathological
Dry eye disease (DED) is a multifactorial disorder that disturbs ocular surface equilibrium, considerably diminishing quality of life. Present therapies only offer symptomatic alleviation. Stem cell treatment, especially mesenchymal stem ce
EXPLORER total body PET scanner is creating a new way to visualize the protective barrier to the brain to reveal impacts from cancer and other diseases.
Capitalizing on the flexibility of tiny cells inside the body鈥檚 smallest blood vessels may be a powerful spinal cord repair strategy, new research suggests.
The Cedars-Sinai Board of Governors Regenerative Medicine Institute is marking its 15th anniversary by further expanding its commitment to research, development of cell-based human models and therapies, and education with three new leadership appointments and the creation of a master鈥檚 degree program.
Recent findings in bone regeneration research, highlights the significant impact of biological sex and donor variability on healing processes, offering promising new approaches to personalized medicine. By modeling cartilage-to-bone transition with innovative callus organoids, scientists discovered two distinct pathways鈥攈ypertrophic cartilage and fibrocartilage鈥攄riven by early progenitor cell activation.
Dr. Gilbert Bernier, a neuroscientist and professor at the University of Montreal who is pushing the boundaries of regenerative medicine.
Mayo Clinic is taking epilepsy research in a bold new direction, exploring treatment approaches to help patients living with the most severe and difficult-to-treat forms of epilepsy. About 50 million people worldwide are impacted by epilepsy. Approximately 30% of patients, or about 15 million people, suffer with drug-resistant epilepsy (DRE).
Longevity Medical Institute鈩� Integrates OncoSeek庐 to Launch One of Mexico's Most Advanced Cancer Screening Programs
Scientists have unveiled a revolutionary method for mass-producing high-quality human mitochondria, potentially transforming treatments for degenerative diseases. By refining stem cell culture conditions, researchers achieved an extraordinary 854-fold increase in mitochondrial production while significantly enhancing energy output.
A new 3D printed customizable hydrogel performed well in preclinical trials with several different types of meniscal tears
Three Tufts faculty members have been named fellows of the American Association for the Advancement of Science, the world鈥檚 largest scientific society. They join 468 other scientists, engineers, and innovators from many scientific disciplines being recognized for their scientific achievements.
Manufacturing engineers are at the forefront of bringing new medicines derived from human sources such as cells, blood and genes to patients. They produce what are often first-of-their kind biotherapies for diseases that previously had few or no treatment options.
A new discovery has shed new light on the crucial role of the CD47 protein in bone fracture healing. Scientists have identified CD47 as an essential regulator of mesenchymal progenitor cell (MSC) proliferation鈥攃ells critical for bone repair. Without CD47, bone healing was significantly delayed, with reduced callus formation and diminished bone volume in both normal and ischemic fracture models. These findings suggest that targeting CD47 could pave the way for novel therapeutic strategies to enhance fracture recovery, particularly in cases where blood supply is compromised.
New Sanford Burnham Prebys scientist Ahmed Mahmoud, PhD, and his team focus on how to repair adult hearts by restoring the regenerative powers they once possessed early in development. He wants to advance the discoveries he has made in regenerating hearts in mice to develop treatments that may one day benefit patients.
A new study has unveiled the potential of hydrogen-bonding crosslinked supramolecular polymer materials derived from N-acryloyl glycinamide (NAGA). These innovative materials exhibit exceptional mechanical strength, self-healing properties, and tunable functionalities, positioning them as versatile solutions for industries ranging from biomedical engineering to flexible electronics and energy storage.
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