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An FDA-designated orphan drug that can target a key vulnerability in lung cancer shows promise in improving the efficacy of radiation treatments in preclinical models, according to a study by UT Southwestern Medical Center researchers. The findings, published in Science Advances, suggest a new way to enhance the response to radiotherapy by inhibiting DNA repair in lung cancer cells.
Traditional methods of studying human gene mutations are often laborious and costly. Now bioengineers at UC San Diego have developed a new simple approach to rapidly check on human gene changes and also screen chemicals as potential drugs by turning everyday bacteria into living test tubes.
After reviewing hundreds of hours of surgical video, a team led by Cedars-Sinai investigators has created a system that links specific steps performed during a surgical procedure to how well patients recover.
Triple-negative breast cancer is a highly aggressive subtype of breast cancer that affects 10% - 15% of all breast cancer patients. According to the American Cancer Society, Black women are more than twice as likely as other ethnic populations to receive a diagnosis of triple-negative breast cancer.
Sustainability issues increasingly impact businesses, including higher costs, risks, and operational disruptions due to extreme weather and other climate change effects. Companies also face ethical concerns about human rights, inequality, pollution, and stakeholder demands for more responsible behavior.
Researchers at Children鈥檚 Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania announced the first ever direct approach to the depletion and replacement of microglia, the native immune cells of the central nervous system (CNS).
Hackensack Meridian Health Hospitals named to 麻豆传媒week's best maternity hospitals
Heavy actinides 鈥� elements at the bottom of the periodic table, after plutonium 鈥� are radioactive, rare and chemically complex, making them notoriously difficult to study.
Two years after receiving an investigational gene therapy as part of a clinical trial co-led by UCLA鈥檚 Dr. Donald Kohn, nine children born with a life-threatening immune disorder are living free of disease symptoms.
People whose biological age is higher than their chronological age may be more likely to develop dementia than people whose biological age matches or is lower than their chronological age, according to a study published on April 30, 2025, online in Neurology庐, the medical journal of the American Academy of Neurology.
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