Physician-in-Chief Emerita; Director, Autoimmunity and Inflammation Research Program
Hospital for Special Surgeryimmune system activation , Lupus, Rheumatoid Arthritis, Rheumatology, Systemic Lupus Erythematosus
Dr. Mary Crow, a rheumatologist, is physician-in-chief emerita at Hospital for Special Surgery and a professor of Medicine in the Division of Rheumatology of the Department of Medicine at Weill Cornell Medical College. She is also director of the Autoimmunity and Inflammation Research Program at HSS and co-director of the Mary Kirkland Center for Lupus Research at the HSS Research Institute. Dr. Crow holds the Benjamin M. Rosen Chair in Immunology and Inflammation Research at HSS. She led the HSS Department of Medicine and the Division of Rheumatology in the Department of Medicine at Weill Cornell from 2010 to 2020. Dr. Crow’s academic and research career has focused on unraveling the cellular and molecular mechanisms that underlie the systemic autoimmune diseases, with a particular focus on systemic lupus erythematosus and rheumatoid arthritis. She has identified interferon-alpha, an immune system protein typically expressed in the setting of virus infection, as a key pathogenic mediator in lupus. Her laboratory continues to study the triggers of immune system activation in SLE, the molecular pathways associated with the clinical manifestations of lupus, and the mechanisms that result in disease flares. Dr. Crow’s research has identified therapeutic targets, providing the rationale for the development of novel therapeutic agents for patients with SLE. In addition to her leadership roles at HSS and WCMC/NYPH, Dr. Crow has served as president of the American College of Rheumatology, as president of the Henry Kunkel Society, and as chair or co-chair of the Scientific Advisory Board of the Alliance for Lupus Research and the Lupus Research Alliance from 2008 to 2019. She has been honored as an “Arthritis Hero” of the Arthritis Foundation, and in 2010 she received the Margaret D. Smith Lifetime Achievement Award of the Arthritis Foundation, New York Chapter. In 2018 she received the Presidential Gold Medal of the American College of Rheumatology, and in 2019 she was honored as a Notable Woman in Healthcare by Crain’s New York Business.
Dermatomyositis, Juvenile Arthritis, Lupus, Osteomyelitis, Uveitis, Vasculitis
Chief of Pediatric Rheumatology at Hospital for Special Surgery (HSS), Karen Onel, MD, cares for children and teens with arthritis and other autoimmune disorders. In particular, she diagnoses and treats: lupus, juvenile arthritis, vasculitis, uveitis (an inflammatory disorder of the eye), chronic non-infectious osteomyelitis, dermatomyositis and the periodic fever syndromes. Her goal is to work with the patient and his/her family to create a long-term care plan that will lead to improved quality of life. Dr. Onel's research focuses on gaining a greater understanding of the causes of rheumatic illnesses, as well as evaluating the safety and tolerability of new treatments. She is collaborating with other institutions to define evidence-based best treatment practices for children with JIA, SLE, and recurrent non-infectious osteomyelitis. Dr. Onel has authored numerous papers, reviews, and book chapters on pediatric rheumatology. In addition, she serves as a reviewer for several scientific journals, including Arthritis and Rheumatism, Lupus, Seminars in Arthritis and Rheumatism, and Pediatric Rheumatology. Pediatrics, Rheumatology