New modeling research challenges public health guidelines that recommend conservative antibiotic use for cholera. In some cases, prescribing antibiotics more broadly could slow or stop outbreaks and even reduce the risk of antibiotic resistance.
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The pathogen that causes tuberculosis is deadly in part because of its complex outer envelope, which helps it evade immune responses of infected hosts. In an ACS Infectious Diseases paper, researchers developed a chemical probe to study a key component of this envelope. Their results provide a step toward finding new ways of inactivating the bacterium.
An experimental drug now in clinical trials as a cancer treatment could help boost the power of first-line tuberculosis (TB) treatments by helping infected cells die a gentler death, Johns Hopkins Medicine investigators report.
UdeM pharmacy professor Simon Matoori has reviewed studies on the therapeutic properties of honey in the treatment of both acute and chronic wounds.
Un estudio publicado en Brain Communications destaca un nuevo enfoque para el tratamiento de la epilepsia resistente a los medicamentos. Los investigadores de Mayo Clinic han desarrollado una plataforma innovadora de estimulaci贸n cerebral profunda (DBS, del ingl茅s Deep Brain Stimulation) que se ha utilizado no solo para reducir las convulsiones, sino tambi茅n para mejorar la memoria y el sue帽o, dos desaf铆os comunes para los pacientes con epilepsia.
Um estudo publicado na Brain Communications destaca uma nova abordagem para o tratamento da epilepsia resistente a medicamentos. Pesquisadores da Mayo Clinic desenvolveram uma plataforma inovadora de estimula莽茫o cerebral profunda ((DBS, do ingl锚s Deep Brain Stimulation) que foi utilizada n茫o apenas para reduzir as crises, mas tamb茅m para melhorar a mem贸ria e o sono 鈥� dois desafios comuns para pacientes com epilepsia.
乇賵鬲卮爻鬲乇貙 賵賱丕賷丞 賲賷賳賷爻賵鬲丕 鈥� 鬲爻賱賾賽胤 丿乇丕爻丞 噩丿賷丿丞 賳購卮乇鬲 賮賷 賲噩賱丞 丕鬲氐丕賱丕鬲 丕賱丿賲丕睾 (Brain Communications) 丕賱囟賵亍 毓賱賶 胤乇賷賯丞 噩丿賷丿丞 賱毓賱丕噩 丕賱氐乇毓 丕賱賲賯丕賵賲 賱賱兀丿賵賷丞. 胤賵賾乇 丕賱亘丕丨孬賵賳 賮賷 賲丕賷賵 賰賱賷賳賰 賲賳氐丞 賲亘鬲賰乇丞 賱賱鬲丨賮賷夭 丕賱毓賲賷賯 賱賱丿賲丕睾 賵丕賱鬲賷 丕爻鬲購禺丿賲鬲 賱賷爻 賮賯胤 賱鬲賯賱賷賱 丕賱賳賵亘丕鬲貙 賵賱賰賳 兀賷囟賸丕 賱鬲丨爻賷賳 丕賱匕丕賰乇丞 賵丕賱賳賵賲 鈥� 賵賴賲丕 鬲丨丿賷丕賳 卮丕卅毓丕賳 賱賲乇囟賶 丕賱氐乇毓.
A new study conducted by researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore has uncovered a key mechanism behind lenalidomide resistance in multiple myeloma (MM), offering new insights into potential strategies for improving treatment outcomes and overcoming drug resistance.
A study published in Brain Communications highlights a new approach to treating drug-resistant epilepsy. Researchers at Mayo Clinic have developed an innovative deep brain stimulation (DBS) platform that was used to not only reduce seizures, but also improve memory and sleep 鈥� two common challenges for patients with epilepsy.
Viruses known as 鈥渏umbo phage鈥� are a new hope against the rising antibacterial infection crisis. Researchers have discovered how jumbo phage are able to infect bacteria so efficiently. They found a compartment that protects and hides valuable DNA material from the bacteria鈥檚 immune defense system.
A research team at Indiana University Bloomington has uncovered new details about how a tiny virus builds its protective outer shell 鈥攁 crucial part of its ability to infect cells.
Antibiotic-resistant bacteria can cause life-threatening infections that are almost impossible to treat with existing medication. As a result, common illnesses such as urinary tract infections or skin wounds are becoming a health risk. Empa researchers are therefore working on sensors that quickly identify resistant germs and recommend efficient treatment.
A small molecule shaped like a lasso may be a powerful tool in the fight against infectious diseases, according to a new study in Nature co-authored by University of Illinois Chicago researchers.
A McMaster University team led by renowned researcher Gerry Wright has identified a strong candidate to challenge even some of the most drug-resistant bacteria on the planet: a new molecule called lariocidin.
Some notoriously difficult to treat infections may not be as resistant to antibiotics as has been thought, according to University of Illinois research using a microfluidic device that more closely duplicates the fluid flow found in the body.
The study, appearing in the March 25 edition of eBioMedicine (open-access journal from The Lancet), found that using intracranial EEG recordings with high-density arrays resulted in better appraisals and better agreement about the location of SOZ among the epileptologists, compared to lower-density recordings.
Irvine, Calif., Feb. 24, 2025 鈥� There鈥檚 an arms race in medicine 鈥� scientists design drugs to treat lethal bacterial infections, but bacteria can evolve defenses to those drugs, sending the researchers back to square one. In the Journal of the American Chemical Society, a University of California, Irvine-led team describes the development of a drug candidate that can stop bacteria before they have a chance to cause harm.
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