麻豆传媒

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More than 100 experts in molecular simulation, coordinated by IRB Barcelona, have published an article in Nature Methods advocating for a paradigm shift in molecular dynamics data management. The article defends the implementation of the FAIR principles (Findable, Accessible, Interoperable, Reusable) to improve the reproducibility of calculations and facilitate their later use as a source of information on the flexibility of biomacromolecules. Led by Drs. Modesto Orozco and Adam Hospital, the article proposes the establishment of a shared infrastructure for storing and reusing data in the context of the AI revolution.

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Unbound Medicine today announced the availability of Assist鈩� on the uCentral鈩� medical platform. Powered by Unbound Intelligence鈩⑩�攚hich combines human expertise with artificial intelligence鈥擜ssist鈩� offers customizable digital assistants designed to serve both clinicians and medical librarians. This advanced capability enables healthcare professionals to quickly find answers to clinical questions and distill medical literature, turning information into insights that improve patient care. Additionally, it saves librarians time, enabling them to better support clinicians and researchers in meeting their clinical and research information needs.

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The global energy system may be faced with an inescapable trade-off between urgently addressing climate change versus avoiding an energy shortfall, according to a new energy scenario tool developed...

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鈥� Phase I trial demonstrates lasting responses and encouraging safety profile in two aggressive thyroid cancer subtypes, suggesting further progress for CAR T cell therapy in solid tumors 鈥� One patient experienced a complete response, and one patient had a partial response 鈥� This type of cancer has limited treatment options, and most patients have a poor prognosis of six months or less 鈥� AIC100 is a CAR T cell therapy that targets the ICAM-1 protein on tumor cells

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A new liquid biopsy approach developed by聽Johns Hopkins Kimmel Cancer Center investigators could revolutionize brain cancer detection by identifying circulating DNA fragments from tumors and immune cells in blood samples, potentially enabling earlier diagnosis.

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The Society for Clinical Trials (SCT) is pleased to announce that the prestigious David Sackett Trial of the Year Award will be presented to 鈥淏linatumomab in Childhood Standard-Risk B-Cell Acute Lymphoblastic Leukemia.鈥�

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Artificial intelligence algorithms have now been combined with traditional laboratory methods to uncover promising drug leads against human enterovirus鈥�71 (EV71), the pathogen behind most cases of hand, foot and mouth disease. The study, published today in Cell Reports Physical Science by researchers at the Perelman School of Medicine at the University of Pennsylvania, showed that reliable antiviral predictions can be made even when only a modest amount of experimental data are available.

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A team of Canadian researchers has developed a curriculum framework to help train future family physicians in the use of artificial intelligence (AI), addressing a critical gap in medical training as digital tools become more common in patient care.

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In Physics of Fluids, researchers have developed a foolproof recipe for cacio e pepe, based on their findings studying the physics of mixing cheese in water and determining the mechanism that causes the cheese sauce to go from creamy to clumpy. The team found that a 2%-3% starch-to-cheese ratio produced the smoothest, most uniform sauce; they recommend using powdered starch, rather than relying on an unknown amount of starch in pasta water.

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The largest sample of galaxy groups ever detected has been presented by a team of international astronomers using data from the James Webb Space telescope (JWST) in an area of the sky called COSMOS Web.

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A new report shows that children learn arithmetic most effectively when instruction combines conceptual understanding and timed practice.

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Compared to laparoscopic cholecystectomies, the rate of needing a second procedure to repair a bile duct injury is high across the board

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Pesquisadores do Centro de Medicina Personalizada da Mayo Clinic descobriram uma variante gen茅tica rara que pode ser a causa direta da doen莽a hep谩tica esteat贸tica associada 脿 disfun莽茫o metab贸lica.

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A recent survey of more than 1,000 U.S. adults showed that nearly all Americans believe sun protection is important, with 1 in 4 citing the influence of a dermatologist as the reason. However, Americans have experienced sun damage at increasing rates since 2020, putting themselves at risk for skin cancer.

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Scientists have identified a key gene that regulates sugar metabolism and dramatically improves tomato fruit quality and resilience after harvest. The gene, known as SlVI, encodes a vacuolar invertase that plays a critical role in converting sucrose into glucose and fructose during fruit ripening. By knocking out SlVI, researchers achieved higher fruit sucrose levels, enhanced firmness, increased resistance to fungal infections, and an extended shelf life. These findings not only reveal new insights into sugar's dual role as both an energy source and signaling molecule but also open avenues for developing tastier and more durable fruits, addressing critical challenges in agriculture and food storage.

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Investigadores del Centro para Medicina Personalizada en Mayo Clinic han descubierto una variante gen茅tica rara que puede ser la causa directa de la enfermedad hep谩tica esteat贸sica asociada a disfunci贸n metab贸lica, anteriormente conocida como enfermedad del h铆gado graso no alcoh贸lico.

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An $11.5 million sponsorship will launch a new research institute at Tufts focused on materials science and engineering. The Tufts Epsilon Materials Institute is a collaboration between manufacturer Epsilon Group and the university to advance innovations in materials that address global challenges in energy and sustainability.