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The ongoing shortage of donor hearts for children who need them stems from multiple causes, including a lack of donor awareness, organ allocation issues, and not enough organs that are of sufficient quality to transplant. Currently, new hearts for kids are still hard to find, and they are even scarcer for babies. Infants are particularly hard to match with a heart.

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A team led by Children鈥檚 Hospital Los Angeles has become the first in the world to demonstrate the possibility of using genetically engineered pig hearts as a potential 鈥渂ridge鈥� to heart transplant for critically ill babies. The groundbreaking preclinical research could lead to a lifesaving alternative for supporting critically ill babies waiting for a new heart鈥攑articularly those with single-ventricle heart disease, most of whom currently die while waiting for a transplant.

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The Society of Thoracic Surgeons (STS) today announced the launch of its latest surgical risk calculator designed for patients undergoing ascending aorta and aortic root surgery, with or without concomitant aortic valve replacement (AVR).

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New research has shown that hypertensive individuals who maintain optimal control of several key health risk factors鈥攕uch as blood pressure, cholesterol, and lifestyle behaviors鈥攃an significantly reduce their risk of dying prematurely. The study found that with each additional risk factor brought under control, the risk of death from cancer, cardiovascular disease, and other causes dropped substantially. Most importantly, those who achieved high levels of joint risk factor control had no greater risk of early death than people without hypertension. This suggests that a comprehensive, multi-pronged approach to managing hypertension could effectively eliminate the excess mortality risk associated with the condition.

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Researchers have developed a new therapy that can be injected intravenously right after a heart attack to promote healing and prevent heart failure. The therapy both prompts the immune system to encourage tissue repair and promotes survival of heart muscle cells after a heart attack.

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Mount Sinai-led research can transform how hospitals triage, risk-stratify, and counsel patients to save lives

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Cardiology faculty practice is the only heart center in New York to receive the Pinnacle of Excellence Award

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The molecular mechanism behind why heart attacks can vary in severity depending on the time of day has been uncovered by researchers at UTHealth Houston, potentially paving the way for innovative treatments that align with the natural circadian rhythm.

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Join 300+ mini-medics as they explore the exciting world of health care with dozens of activities designed to help shape the next generation of lifesavers.

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Mount Sinai-led research can transform how hospitals triage, risk-stratify, and counsel patients to save lives

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Children鈥檚 Hospital Los Angeles experts are set to speak at nearly 80 sessions and poster presentations at the 2025 Pediatric Academic Societies (PAS) meeting April 24-28 in Honolulu.

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Every eight minutes, someone joins the transplant waiting list in the United States, and just one organ donor can save up to eight lives. Penn State Health experts tell how registering as an organ donor can give others a second chance at life.

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Researchers from Children鈥檚 Hospital Los Angeles and the USC Viterbi School of Engineering have received key funding to support their work on a novel device: an artificial right atrium for patients with a Fontan circulation. The investigators鈥擟ynthia Herrington, MD, and Andrew Cheng, MD, of CHLA, and Niema Pahlevan, PhD, of USC鈥攔eceived the USC Nemirovsky Engineering and Medicine Opportunity (NEMO) Prize.

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FDA Approves WiSE庐 System, World's First and Only Leadless Left Ventricular Endocardial Pacing (LVEP) Device for CRT

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An artificial intelligence (AI) program trained to review images from a common medical test can detect early signs of tricuspid heart valve disease and may help doctors diagnose and treat patients sooner, according to research from the Smidt Heart Institute at Cedars-Sinai.

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Major reallocation of healthcare services during the COVID-19 pandemic meant that elective surgery in children with congenital heart disease (CHD) was significantly reduced, so that those needing urgent, lifesaving and emergency surgery could be treated.

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Innovative technology could help detect early heart disease through synthetic echocardiograms.